Analgesic Effects of Caudal S-ketamine for Supplementation of Ropivacaine Caudal Analgesia in Children With Hypospadias

Launched by TAO ZHANG · Jun 27, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at the effects of a medication called S-ketamine when added to a common pain relief method known as caudal analgesia, which uses another medication called ropivacaine. This trial focuses on children undergoing surgery for a condition called hypospadias, which affects the urinary tract. The main goal is to see if adding S-ketamine helps to relieve pain for a longer time after surgery without causing unwanted side effects.

To participate, children must be between 3 months and 18 years old, weigh less than 28 kg, and have parental consent. They should be scheduled for elective hypospadias surgery and be in good health (classified as ASA I or II, which means they are generally healthy with minor issues). However, children with certain medical conditions or sensitivities, such as spinal abnormalities or clotting disorders, will not be eligible to join. If your child is selected for this study, they will receive either the S-ketamine or a placebo (an inactive substance) during their surgery, and the research team will monitor their pain relief after the procedure.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • informed parent consent, ASA I or II children, between 3months and 18 years of age,and weighing \<28kg, scheduled for elective hypospadias surgery with general anesthesia will be recruited.
• Exclusion Criteria:
• • Patients who have congenital abnormalities of lower spine and meninges.
• • Patients with hypersensitivity to any local anesthetics
• • Children with coagulation disorders
• • Presence of Infections at puncture sites
• • Preexisting neurological disease
• • Refusal to consent by parent/guardian