Characterization of Gastric Evoked Potentials

Launched by UNIVERSITY OF PITTSBURGH · Jun 26, 2023

Keywords

ClinConnect Summary

This clinical trial is exploring a new way to better understand how the stomach responds to brain signals, using a method called Transcranial Magnetic Stimulation (TMS). Essentially, the researchers want to find the best techniques to measure these stomach signals safely, which could help in understanding how the brain and stomach communicate. The study is currently recruiting participants aged between 18 and 65 who are generally healthy.

To be eligible for this trial, participants should not have any significant mental health issues, a history of serious head injuries, or conditions that might interfere with the study, like diabetes or certain neurodegenerative disorders. Those with specific medical devices, current use of certain medications, or a high body mass index (BMI) are also not eligible. If you join the study, you can expect a non-invasive procedure where your brain is stimulated in a way that does not involve any surgery. This could be an exciting opportunity to contribute to important research that might help improve our understanding of how the brain and stomach work together.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • -
• Exclusion Criteria:
• • psychosis or altered cognitive status
• • history of head injury, metal in the skull, stroke, or a history of seizures, loss of consciousness or syncope
• • implantable devices, such as a pacemaker or nerve stimulator
• • current use of antiepileptic medications or current use of the following medications or substances which are known to lower the seizure threshold: Clozapine (Clozaril), Chlorpromazine (Thorazine), amphetamines or methamphetamine, Ecstasy, Ketamine, Angel Dust/PCP, cocaine, or 3 or more alcoholic drinks per day
• • pregnancy
• • BMI \> 30
• • history of bariatric surgery such as sleeve gastrectomy or Roux-en-Y gastric bypass
• • diabetes
• • suffering from a neurodegenerative disorder.