Examining the Role of Female Endogenous Sex Hormones in Eccentric Exercise
Launched by UNIVERSITY OF SOUTHERN CALIFORNIA · Jun 28, 2023
Trial Information
Current as of June 26, 2025
Not yet recruiting
Keywords
ClinConnect Summary
This clinical trial is looking at how female hormones, specifically estrogen and progesterone, can affect how women feel during and after challenging exercises, like downhill running. The researchers want to understand if the levels of these hormones change throughout a woman's menstrual cycle and how that might influence their ability to exercise, how hard they find it, and how quickly they recover afterward.
To participate in this study, women aged 18 to 35 who have a body mass index (BMI) between 18.5 and 29.9 and have regular menstrual cycles are encouraged to join. Participants should not be taking hormonal contraceptives or any other medications that could affect their reproductive health. Those who have certain health conditions, are pregnant, or are experienced runners will not be eligible. If you join, you can expect to take part in exercises while researchers monitor your hormone levels and how you feel during the workouts. This study is not yet recruiting, so keep an eye out for updates if you're interested!
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • 18-35 years of age
- • BMI of 18.5-29.9 as a BMI below or above these cut points results in highly varied menstrual cycle lengths \[15\]
- • Not taking contraception or other types of medication that could influence reproductive status
- • Regular menstruation
- • Non-pregnant
- • Medically free from chronic diseases
- • Novel to downhill running
- • Weight greater than or equal to 110 lbs
- • Not taking exogenous hormones
- • Not suffering from known gynecological disease (i.e., PCOS, endometriosis, etc.) that may influence menstrual cycle regularity
- Exclusion Criteria:
- • Amenorrhea or oligomenorrhea
- • Perimenopausal or menopausal
- • Recreational or professional trail or downhill runner
- • On a form of contraception
- • Cardiac disability
- • Pacemaker
- • Arterial disease
- • Uncontrolled hemorrhage
- • Blood clots
- • Pregnant or trying to become pregnant
- • Cancerous lesions
- • Sensory or mental impairment
- • Unstable fractures
- • Weight less than 110 lbs
- • Suffering from gynecological disease (i.e., PCOS, endometriosis, etc.) that may influence menstrual cycle regularity
- • Taking exogenous hormones
About University Of Southern California
The University of Southern California (USC) is a prestigious research institution located in Los Angeles, California, known for its commitment to advancing knowledge and innovation in various fields, including medicine and health sciences. As a clinical trial sponsor, USC leverages its extensive resources, interdisciplinary expertise, and state-of-the-art facilities to conduct cutting-edge research aimed at improving patient outcomes and public health. The university fosters collaboration among its diverse faculty and students, ensuring a dynamic environment for the development and implementation of clinical studies that adhere to the highest ethical and scientific standards. Through its clinical trials, USC aims to contribute to the advancement of medical science and the translation of research findings into practical applications that benefit communities locally and globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported