Contribution of Residual Tumour DNA Testing on the Surgical Bed

Launched by CENTRE HENRI BECQUEREL · Jun 29, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to check for leftover cancer DNA in patients who have had surgery to remove squamous cell carcinoma from the mouth. The researchers want to see if testing for this DNA in the area where the tumor was removed can provide important information about the cancer and help improve treatment decisions.

To be part of the study, participants need to be at least 18 years old and have a specific type of oral cancer that can be treated with surgery. They also need to be signed up for a social security plan. However, some people won't be able to join, such as those who have had previous radiation to the neck, are pregnant or breastfeeding, or have certain mental or social challenges. The trial is not yet recruiting participants, so there will be more information available soon for those who might be interested in taking part.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Signed informed consent
• • Patient with T1 to T4 squamous cell carcinoma of the oral cavity, regardless of lymph node status (all N) M0, operable
• • 18 years of age or older
• • Member or beneficiary of a social security scheme.
• Exclusion Criteria:
• • Absence of signed informed consent
• • Patient of protected age
• • Psychosocial problems
• • Not affiliated to or benefiting from a social security scheme
• • Previous cervical irradiation
• • Pregnant or breast-feeding women
• • Patient unable to understand the study for any reason or to comply with the constraints of the trial (language, psychological, geographical problems, etc.).