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Search / Trial NCT05935306

Effect of Photobiomodulation to Reduce Post-operative Pain After Endodontic Surgery

Launched by UNIVERSITY OF NOVE DE JULHO · Jul 6, 2023

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying whether a treatment called photobiomodulation (PBM) can help reduce pain after endodontic surgery, which is a type of dental surgery aimed at treating problems in the tooth's root. In this study, 34 patients who need this surgery on their upper jaw will be divided into two groups. One group will receive the actual PBM treatment right after surgery and again 24 hours later, while the other group will receive a simulated treatment that does not provide the same benefits. Both groups will also follow standard procedures for pain management.

To be eligible for this study, participants should be between 18 and 70 years old, have specific types of dental lesions, and be in good health without any other serious medical conditions. Participants can expect to be monitored for pain levels and any side effects over the week following their surgery, with follow-up X-rays to check the healing process. This trial is important because it seeks to find ways to improve pain relief for patients undergoing dental surgery, which can help enhance their recovery experience.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria
  • :• Patients with periapical lesions who have already undergone endodontic treatment (lesions smaller than 10mm in their greatest diameter - Metin et al., 2018, single and chronic lesions)
  • Patients with not comorbidities,
  • Age from 18 to 70 years,
  • Both genders,
  • Healthy permanent teeth with good hygiene.
  • Exclusion Criteria:
  • Who are taking drugs that affect bone metabolism and the inflammatory process (for example: corticosteroids, bisphosphonates),
  • Smokers, pregnant or lactating women,
  • Who used anti-inflammatory drugs in the last 3 months before surgery.
  • Who for any reason interrupted the evolution of the treatment for not attending joint appointments.
  • Patients who do not follow the guidelines or have an injury in the acute phase (pain, edema, exudate)

About University Of Nove De Julho

The University of Nove de Julho (UNINOVE) is a prestigious educational institution located in São Paulo, Brazil, renowned for its commitment to advancing research and innovation in the field of health sciences. As a clinical trial sponsor, UNINOVE aims to foster collaboration between academia and the healthcare industry, facilitating the development and evaluation of novel therapeutic interventions. With a robust infrastructure and a team of experienced researchers, the university is dedicated to conducting high-quality clinical trials that adhere to rigorous ethical standards and regulatory guidelines, ultimately contributing to improved health outcomes and the enhancement of medical knowledge.

Locations

São Paulo, Sp, Brazil

Montevideo, , Uruguay

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported