Multi-domain Intervention Program for Post-stroke Bone Health in Older Adults (BOUNCE)

Launched by HOSPITAL PENGAJAR UNIVERSITI PUTRA MALAYSIA · Jul 1, 2023

Keywords

ClinConnect Summary

The BOUNCE trial is a research study aimed at understanding how to improve bone health in older adults who have had a stroke. Specifically, the trial will compare two groups of participants: one will receive standard care, while the other will participate in the BOUNCE program, which includes activities like exercise and keeping track of their food intake. Researchers want to see if this program helps improve bone density, which is important for preventing fractures, and whether it reduces the chances of falling. They will also gather feedback from participants and healthcare providers about their experiences with the program.

To join the study, participants need to be 50 years or older and have had a stroke diagnosed by a neurologist within the last 90 days. They should be able to walk with or without assistance and undergo a specific bone scan called a DXA scan. However, those with certain serious health issues, such as severe depression or chronic kidney disease, won’t be eligible. If you take part in this trial, you can expect to be monitored for changes in bone health over six months while also sharing your experiences with the program. This study is currently looking for volunteers to help improve care for older adults recovering from strokes.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged 50 years old and older
• • Neurologist diagnosed acute stroke within 90 days
• • Has baseline biochemical test upon admission to the ward
• • Able to undergo DXA scan
• • Modified Rankin Score of 2 to 3
• • Able to walk with or without aids
• Exclusion Criteria:
• • Known underlying malignancy
• • Known major depression or severe psychological illness
• • Known chronic kidney disease stage 3b (eGFR \<45ml/min/1.73m2) or more
• • Taken oral glucocorticoids therapy for at least three months
• • Presence of cognitive impairment (ECAQ \<7)
• • Presence of coronary artery syndrome or congestive cardiac failure
• • Presence of an uncontrolled respiratory condition
• • Underlying malabsorption syndrome
• • Underlying conditions other than stroke that impairs mobility (eg Severe Osteoarthritis, Parkinson's Disease, Multiple sclerosis)
• • Known osteoporosis or fragility fracture
• • Serum phosphate or calcium abnormalities
• • Discharge to a nursing home or rehabilitation centre
• • Already a participant in another trial/study