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Search / Trial NCT05940012

Specific and Shared Mechanisms Associated With Treatment for Chronic Neck Pain

Launched by DUKE UNIVERSITY · Jul 3, 2023

Trial Information

Current as of June 27, 2025

Recruiting

Keywords

ClinConnect Summary

This clinical trial is studying how different types of physical therapy treatments can help people with chronic neck pain, a condition that can cause ongoing pain and difficulty in daily activities. The researchers are particularly interested in comparing two approaches: manual therapy (hands-on techniques) and exercise-based therapy. They want to understand the specific ways each treatment works and also look for common factors that might play a role in how well these treatments help, even though they are different. This study is important because it may reveal whether the success of these treatments is mainly due to unique methods or shared benefits that both provide.

To participate in the trial, individuals must be 18 years or older and have experienced chronic neck pain for at least three months, which is defined as pain that occurs most days and scores 3 or higher on a scale of 1 to 10. Certain people, such as those with a history of neck surgery or specific medical concerns, won't be eligible. Participants can expect to engage in either manual therapy or exercise-based therapy and will contribute to valuable research that could improve treatment options for chronic neck pain in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Individuals with chronic neck pain (chronic pain is defined using the International Association of the Study of Pain (IASP) pragmatic criteria of pain lasting for 3 months or more that cannot be attributed to another diagnosis or condition.)
  • 18 years of age and older
  • experience ongoing neck pain of ≥3 on a 10-point scale for most days of the previous 3-months.
  • Exclusion Criteria:
  • Individuals with cervical pain and suspected radicular symptoms
  • a history of neck surgery within 1 year
  • current or suspected red flags
  • unable to speak or write in English.

About Duke University

Duke University, a leading academic and research institution located in Durham, North Carolina, is renowned for its commitment to advancing healthcare through innovative clinical research. With a strong emphasis on interdisciplinary collaboration, Duke conducts a wide array of clinical trials aimed at developing cutting-edge therapies and improving patient outcomes across various medical fields. The university's Clinical Research Institute provides comprehensive support for trial design, implementation, and regulatory compliance, ensuring that all research adheres to the highest ethical and scientific standards. Duke’s dedication to translating research findings into effective clinical practices underscores its role as a pivotal contributor to the global medical community.

Locations

Philadelphia, Pennsylvania, United States

Charleston, South Carolina, United States

Patients applied

0 patients applied

Trial Officials

Chad E Cook

Principal Investigator

Duke University

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported