Early Detection of Alzheimer's Disease and Affective Disorders by Automated Voice and Speech Analysis (PLATA)

Launched by CENTRE HOSPITALIER UNIVERSITAIRE DE NICE · Jul 5, 2023

Keywords

ClinConnect Summary

The PLATA trial is studying how we can detect early signs of Alzheimer's disease by analyzing people's voices and speech patterns. Researchers are trying to develop a computer program that can identify specific vocal traits, called biomarkers, that may indicate the presence of Alzheimer's. This study is important because if successful, it could mean that patients won't have to go through more invasive tests, like spinal taps or brain scans, to find out if they have this condition.

To participate in the trial, you need to be at least 50 years old and have a known diagnosis related to Alzheimer’s, with mild cognitive issues or no cognitive problems at all. You'll also need to understand the study information and be willing to participate. If you have hearing problems or are under legal protection that prevents you from making your own decisions, unfortunately, you won't be able to take part. If you join, you'll help researchers learn more about how speech can help in the early detection of Alzheimer's disease, which could lead to better, less invasive testing methods in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age ≥ 50 years
• • Diagnosis relevant biomarker and neuropsychological data already available
• • Cognitively healthy to very mild dementia (CDR score max. 0.5)
• • Sufficient knowledge of the study language to understand study information, non opposition form,and questionnaires
• • Expression of non opposition
• Exclusion Criteria:
• • Hearing problems
• • Patient protected by law, under guardianship or curator ship, or not able to participate in a clinical study according to the article L.1121-16 of the French Public Health Code