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Search / Trial NCT05948800

Impact of Nasal Isotonic Solution Irigation on Healthy Athletes' Nasal Flow and Nasal Obstruction Exercise Outcomes

Launched by UNIVERSITY HOSPITAL SESTRE MILOSRDNICE · Jul 9, 2023

Trial Information

Current as of June 24, 2025

Recruiting

Keywords

Nasal Irrigation Isotonic Solution Nose Questionnaire Peak Inspiratory Nasal Flow Excercise

ClinConnect Summary

This clinical trial is studying how using a nasal spray made from isotonic seawater can help improve breathing for healthy athletes. When athletes exercise, they often experience nasal obstruction, which makes it harder to breathe and can affect their performance. The researchers want to find out if rinsing the nose with this seawater solution can enhance airflow and reduce the feeling of nasal blockage during physical activity.

To participate in the study, individuals need to be healthy adult athletes aged 18 to 35. However, those with recent nasal infections, significant nasal deformities, or who have had nose surgery within the last month won't be eligible. Participants will be asked to use the nasal spray and share their experiences regarding their breathing during exercise. The trial is currently recruiting participants, and it aims to learn more about how this simple treatment might help athletes breathe better while they train or compete.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • 50 healthy adult athletes between the ages of 18 and 35 will be engaged in the research (power analysis with 80% power and an alpha error of 5% shows that 32 subjects in two groups are sufficient).
  • Exclusion Criteria:
  • Bacterial or viral acute inflammation of the upper respiratory system, chronic obstruction of one or both nostrils with significant deformation of the septum, surgery on the nose or nasal septum within one month of the start of the study

About University Hospital Sestre Milosrdnice

University Hospital Sestre Milosrdnice is a leading healthcare institution located in Zagreb, Croatia, renowned for its commitment to advanced medical research and high-quality patient care. The hospital serves as a pivotal center for clinical trials and innovative therapeutic approaches, leveraging its multidisciplinary expertise to enhance patient outcomes and contribute to the global medical community. With a strong emphasis on ethical standards and regulatory compliance, the institution fosters collaboration among researchers, healthcare professionals, and academic partners, aiming to translate scientific discoveries into effective treatments and improve healthcare practices.

Locations

Zagreb, , Croatia

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported