Probiotics and Insulin Resistance in Obese Asthmatics

Launched by UNIVERSITY OF ALABAMA AT BIRMINGHAM · Jul 7, 2023

Keywords

ClinConnect Summary

Participants for this study will be recruited through the UAB Asthma Clinic under an IRB approved protocol. The Asthma Clinic at UAB has over 350 unique patients. The composition of the clinic is 73% female, 58% non-hispanic white and 34% black/African American, and 63% have a BMI over 30. Asthma is defined by a constellation of symptoms including episodic dyspnea, cough, wheeze, and chest tightness with evidence of airway hyperresponsiveness. The subjects recruited to this study will be seen in the Asthma Clinic at UAB. All participants will have a clinical history of symptoms consistent w...

Gender

ALL

Eligibility criteria

• InclusionCriteria:
• • Age \> 18 years
• • All patients will be obese asthmatics. Patients will have a body mass index \>30 and insulin resistance\>5.
• • Asthmatics who have stable disease without changes to their asthma related medications for 3 months prior to enrollment
• Exclusion Criteria:
• • Asthma related hospitalization within 90 days of enrollment
• • Asthma exacerbation requiring \>3 days of oral corticosteroids within 28 days of enrollment
• • Comorbid lung diseases other than asthma
• • Pregnancy or planned pregnancy
• • Inability to understand study procedures and/or provide informed consent
• • Other significant medical conditions based on discretion of PI