Effects of Lead Exposure on Ferroptosis Pathway

Launched by NORTHERN JIANGSU PEOPLE'S HOSPITAL · Jul 11, 2023

Keywords

ClinConnect Summary

This clinical trial is looking into how long-term exposure to lead, particularly among workers in lead acid battery factories, affects iron metabolism in the body and a specific process called ferroptosis, which is a type of cell death related to iron. Researchers want to understand if and how lead exposure can lead to neurotoxicity, which means potential harm to the nervous system. The study is currently recruiting participants who are over 18 years old and have worked in a lead acid battery factory for more than 10 years.

To be eligible, individuals should not have any neurological disorders, endocrine (hormonal) diseases, cancer, or prior exposure to other harmful chemicals. Participants can expect to contribute to important research that could help improve understanding of the health risks associated with lead exposure. This study aims to gather valuable information that could lead to better safety measures for workers in industries where lead is present.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Aged over 18 years old
• • 2. Work for the lead acid battery factory more than 10 years
• Exclusion Criteria:
• • 1. Neurological disorders
• • 2. Endocrine diseases
• • 3. Cancer
• • 4. Exposure to any chemical pollutant before