RENAL: TNF-alpha Inhibitor for Improving Renal Dysfunction and Primary Graft Dysfunction After Lung Transplant

Launched by NORTHWESTERN UNIVERSITY · Jul 10, 2023

Keywords

ClinConnect Summary

After being informed about the study and potential risks, all patients giving written consent who undergo a lung transplant will be randomized in a 1:1 ratio to either the treatment or control group. Patients randomized to the treatment group will receive one dose of the study drug, Etanercept, via subcutaneous injection just prior to the lung transplant. Patients randomized to the control group will not receive Etanercept. Both groups will receive standard lung transplant care after implantation.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Planning to undergo transplantation of the lung at Northwestern Memorial Hospital.
• • Willing and able to read, understand, and be capable of giving informed consent.
• Exclusion Criteria:
• • Previous or current use of TNFa antibody.
• • Any condition that, in the opinion of the attending physician, would place the patient at undue risk by participating.