The Impact of Sleep Restriction on Gastric Emptying, Appetite and Energy Intake

Launched by NORTHUMBRIA UNIVERSITY · Jul 11, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how not getting enough sleep affects our bodies, particularly in people who are dealing with obesity. Researchers want to find out if sleeping less changes how our stomach empties, how hungry we feel, and how much food we eat. They are looking for healthy adults between the ages of 18 and 45 who typically sleep 7 to 9 hours a night. Participants should not be pregnant, smoke, or drink too much alcohol or caffeine. They also shouldn't have certain health issues that might affect the study.

If you decide to join this trial, you'll undergo some health screenings to ensure you meet the eligibility requirements. Throughout the study, you will be asked about your sleep patterns and appetite. This research could help us understand the link between sleep and eating behaviors, which is important for managing obesity. If you’re interested in contributing to this important research, you might be a great fit!

Gender

ALL

Eligibility criteria

• • Inclusion
• • 1. Healthy (As assessed with medical screening questionnaire)
• • 2. Self-reported habitual bedtimes between 7 to 9 hours (As assessed with the Pittsburgh sleep quality index)
• • 3. Between the ages of 18 to 45
• • Exclusion
• • 1. Participants will also be excluded from participation if they are pregnant.
• • 2. Current smokers
• • 3. Excessive alcohol (\>2 drinks per day)
• • 4. Excessive caffeine (\>300mg per day)
• • 5. Musculoskeletal injury.
• • 6. Shift work during the past 4 weeks
• • 7. Travel across more than one time zones during the past 4 weeks.
• • 8. An indication of having a depressed mood (As assessed by a score on the Centre for Epidemiologic Studies of Depression scale above 16).
• • 9. Moderately or highly physically active, as determined by the International Physical Activity Questionnaire (IPAQ) short form.
• • 10. Excessive daytime sleepiness as measured by the Epworth Sleepiness Scale (Score \> 10) (ESS) (Hart et al., 2015).
• • 11. Participants will also be considered ineligible if they achieve a score indicative of narcolepsy or chronic insomnia, as assessed through the Pittsburgh Sleep Quality Index \[PSQI\] (Score \> 5) (Hart et al., 2015).
• • 12. Participants must achieve a score \< 50 on the Food Craving Questionnaire-Trait-reduced (FCQ-T-r), which has been shown to discriminated between individuals with and without "food addiction" with high sensitivity (85%) and specificity (93%) (Meule et al., 2014).