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Search / Trial NCT05953376

Empiric Calcium in Massive Transfusion

Launched by UNIVERSITY OF CALIFORNIA, IRVINE · Jul 11, 2023

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

ClinConnect Summary

This clinical trial, called “Empiric Calcium in Massive Transfusion,” is investigating whether giving calcium through an IV (intravenous) can help patients who have lost a lot of blood due to trauma. Calcium is important because it helps blood clot, which can stop bleeding. The researchers want to find out if giving calcium right away can reduce the need for blood transfusions, lower the use of medications that support blood pressure, and ultimately help patients survive after serious injuries.

The trial is looking for trauma patients who are receiving a massive blood transfusion. To be eligible, participants must not be pregnant, must not have certain medical conditions like high calcium levels or hemophilia, and cannot be prisoners. If someone meets these criteria and participates in the study, they can expect to receive standard care along with the calcium treatment being tested. This study is important because it could potentially improve outcomes for patients who are critically injured and losing a lot of blood.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Trauma patients receiving massive transfusion protocol
  • Exclusion Criteria:
  • Pregnancy
  • Prisoners
  • Known history of hypercalcemia
  • Active hyperparathyroidism
  • Hemophilia

About University Of California, Irvine

The University of California, Irvine (UCI) is a leading research institution renowned for its commitment to advancing health and medical knowledge through innovative clinical trials. With a robust infrastructure for clinical research, UCI fosters interdisciplinary collaboration among its esteemed faculty and researchers, aiming to translate scientific discoveries into effective therapeutic solutions. The university prioritizes ethical standards and participant safety while addressing critical healthcare challenges across various fields, including cancer, neurology, and public health. UCI's dedication to excellence in research and education positions it as a pivotal contributor to the advancement of clinical science and patient care.

Locations

Patients applied

0 patients applied

Trial Officials

Jeffry Nahmias, MD

Principal Investigator

University of California, Irvine

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported