Detection of Ileoanal Pouch/Reservoir Adenomas

Launched by JEAN CHRISTOPHE SAURIN · Jul 11, 2023

Keywords

ClinConnect Summary

This clinical trial is exploring a method to better detect adenomas, which are abnormal growths that can develop into cancer, in patients who have had surgery for familial adenomatous polyposis. These patients often have an ileal pouch, a type of surgical reservoir created after removing the colon. The researchers believe that using a special dye called indigo-carmine during a procedure called chromoendoscopy will help spot these adenomas more easily, especially since they can be flat and tricky to find.

To participate in the trial, candidates must have familial adenomatous polyposis and an ileo-anal anastomosis with a pouch reservoir. They also need to have a high-quality preparation for the procedure. If you or a loved one meets these criteria, you may have the opportunity to be part of this important study, which aims to improve cancer screening and potentially lower cancer risks for this group of patients. Participants can expect to undergo procedures with the indigo-carmine dye, which could enhance the detection of adenomas.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients with familial adenomatous polyposis
• • Ileo-anal anastomosis with pouch reservoir
• • Quality of the final preparation = 3 (excellent) on the studied area
• • Films made under optimal conditions for the 3 staining methods
• Exclusion Criteria:
• • Patient with no familial adenomatous polyposis
• • Patient without Ileo-anal anastomosis reservoir
• • Insufficient quality of the final preparation \<3
• • Absence of films made under optimal conditions for the 3 staining methods