A Multi-Modal Remote Monitoring Platform for Frontotemporal Lobar Degeneration (FTLD) Syndromes

Launched by MASSACHUSETTS GENERAL HOSPITAL · Jul 14, 2023

Keywords

ClinConnect Summary

This clinical trial is focused on studying a new way to monitor the symptoms of a condition called Progressive Supranuclear Palsy (PSP), which is a type of frontotemporal lobar degeneration. Researchers are looking to enroll about 60 patients with PSP over two years and will track each participant's progress for a full year. The goal is to develop a reliable system for monitoring not just PSP but also other similar conditions that affect the brain.

To be eligible for this study, participants need to have a confirmed diagnosis of PSP, be able to walk a short distance without help, and have someone, like a caregiver, who can assist them throughout the study. Participants should also be comfortable reading and speaking in English. However, those with certain health issues or a history of frequent falls may not qualify. If you or someone you know is interested, the study offers a chance to contribute to important research while receiving close monitoring of symptoms.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Clinical diagnosis of possible or probable PSP as defined by the 2017 MDS criteria
• • Fluent in reading and speaking English and capable of providing informed consent based on the principal investigator's judgement
• • Able to walk 10 feet unassisted at the time of initial enrollment
• • Must have a caregiver or study partner who is willing and able to assist with all study-related procedures
• Exclusion Criteria:
• • Any neurological, medical, or psychiatric condition that would preclude participation in study activities based on the investigator's judgment.
• • A history of frequent falls defined as more than 5 falls per month, or who require a walker to ambulate safely at baseline will not be eligible to participate in the study.