Fluid Responsiveness in Post-cardiac Surgery

Launched by TANTA UNIVERSITY · Jul 21, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how to better predict if patients who have just had heart surgery need extra fluids to help their recovery. Researchers are specifically looking at two tests that measure how the heart and lungs respond to breathing changes and fluid challenges. The goal is to find out if these tests can help doctors make safer and more effective decisions about fluid management in patients right after heart surgery.

To participate in this study, you need to be at least 18 years old and on a breathing machine after having cardiac surgery, such as a bypass or valve repair. You should also have a healthy heart function and be following a specific breathing strategy. If you’re not breathing on your own or have serious complications after surgery, you might not be eligible to join. If you do participate, you can expect to undergo some tests that will help doctors better understand how your body responds to fluids after surgery. This information could lead to improved care for future patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients on mechanical ventilation
• • Patients ≥18 years of age
• • patients undergoing cardiac surgery (coronary artery bypass graft, valve repair/ replacement, combined cardiac surgery)
• • patients with normal systolic function of the left and right ventricle
• • patient is mechanically ventilated with a protective lung strategy
• Exclusion Criteria:
• • Patients with Spontaneously breathing activity
• • Patients undergoing emergent cardiac surgery.
• • Patient with severe peripheral arterial occlusive disease
• • Pregnant women
• • Contraindication of passive leg raising test
• • unstable post-operative course
• • Post-operative complications such as uncontrolled bleeding, severe neurologic impairment, or accidental mechanical complications;
• • presence of residual severe tricuspid or any valvular regurgitations
• • low cardiac output, low ejection fractions (EF ≤45%)
• • open chest,Pao2/Fio2 ≤ 200