Application of Lung Near-Infrared Spectroscopy (NIRS) in Preterm Infants

Launched by KECK SCHOOL OF MEDICINE OF USC · Jul 18, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the use of a special device called Near-Infrared Spectroscopy (NIRS) to measure oxygen levels in the lungs and brain of premature infants who are facing breathing difficulties, known as Respiratory Distress Syndrome. The goal is to see how effectively the NIRS can track oxygen levels in the lungs compared to the brain in babies born between 23 and 32 weeks of pregnancy who need help with breathing and treatment to improve their lung function.

To be eligible for this study, infants must be admitted to the Neonatal Intensive Care Unit and require non-invasive breathing support and a treatment called Surfactant Replacement Therapy. Unfortunately, babies who do not need respiratory help or have certain birth defects cannot participate. Those who do take part will have a small sensor placed on them for about six hours to continuously monitor their oxygen levels before and after receiving surfactant treatment. This will help doctors understand how well the treatment is working and improve care for future babies.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Infants born between 23-32 weeks of gestation admitted to the Neonatal Intensive Care Unit with respiratory distress receiving non-invasive ventilation and requiring Surfactant Replacement Therapy.
• Exclusion Criteria:
• • Neonates with no need for respiratory support/Surfactant. Neonates with congenital malformations.