RESPONSE-2-PAD to Reduce Sedentary Time in Peripheral Arterial Disease Patients

Launched by NATIONAL INSTITUTE FOR PREVENTION AND CARDIOVASCULAR HEALTH, IRELAND · Jul 18, 2023

Keywords

ClinConnect Summary

The RESPONSE-2-PAD trial is studying ways to help patients with Peripheral Arterial Disease (PAD) reduce their sedentary time, which means the time spent sitting or lying down without much activity. The program includes online education, reminders to get up and move, and health coaching to encourage more movement throughout the day. This is particularly important for people with PAD, as staying active can improve their health and quality of life.

To be eligible for the trial, participants must be adults aged 18 or older who have been diagnosed with PAD, which can be confirmed through specific tests that measure blood flow in the legs. Participants should be able to understand and speak English and provide informed consent to join the study. However, those with severe mobility issues, significant PAD symptoms like pain while resting, or certain health conditions that might limit participation are not eligible. If you join the trial, you can expect support and guidance to help you move more and lead a healthier lifestyle.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Adults (≥18 years),
• 2. Symptomatic patients with established peripheral arterial disease. PAD is confirmed by any of the following:
• • Ankle-brachial index (ABI) of less than 0.90 in at least one lower extremity
• • Toe brachial index of less than 0.60
• • Arterial occlusive disease in one lower extremity by duplex ultrasonography, computed tomographic angiography or magnetic resonance angiography.
• • 3. Willing and able to give informed consent.
• • 4. Can read and speak English.
• Exclusion Criteria:
• • 1. patients with significant PAD in the form of rest pain.
• • 2. Any impairments that severely affect mobility (e.g., wheelchair bound).
• • 3. Cognitive impairments revealed by medical records.
• • 4. Significant comorbid disease that would significantly impair the ability to participate in activity.
• • 5. Pregnant / lactating females.