HNC: Human Neural Circuits Electrophysiology During Cognition

Launched by STANFORD UNIVERSITY · Jul 18, 2023

Keywords

ClinConnect Summary

The clinical trial titled "HNC: Human Neural Circuits Electrophysiology During Cognition" is exploring how ketamine, a medication often used for depression, causes feelings of detachment or dissociation in people. Researchers want to learn more about the brain's activity during these experiences, which can help improve treatments for psychiatric disorders.

To participate in this study, individuals must be at least 18 years old and currently receiving care in the clinical neuro inpatient units at Stanford Medical Center. Women who join the trial need to use a reliable birth control method throughout the study. However, people with a history of serious mental health issues, those who are pregnant or nursing, or anyone who has had a bad reaction to ketamine in the past are not eligible. If selected, participants will undergo assessments to observe how ketamine affects their brain and cognition. This research is crucial for understanding the effects of ketamine and potentially improving care for those with mental health conditions.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient in clinical neuro inpatient units at Stanford Medical Center
• • Age \>18 years old
• • Female participants are expected to use an effective method of birth control throughout the study which includes: hormonal methods (birth control pills, patches, injections, vaginal ring or implants), barrier methods (condom or diaphragm) used with spermicide, intrauterine device (IUD), or abstinence (no sex)
• Exclusion Criteria:
• • Lifetime psychotic disorder
• • Pregnant or nursing females
• • Prior adverse ketamine response
• • Use of ketamine in past 7 days