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Search / Trial NCT05962619

Arthrocentesis Alone Versus Arthrocentesis With Hyaluronic Acid Injection

Launched by ASSIUT UNIVERSITY · Jul 25, 2023

Trial Information

Current as of June 26, 2025

Not yet recruiting

Keywords

ClinConnect Summary

This clinical trial is studying two different treatments for a condition called Temporomandibular Joint Dysfunction Syndrome, which can cause pain and difficulty in moving the jaw. The researchers want to compare the effects of a procedure called arthrocentesis, where fluid is removed from the joint, to arthrocentesis combined with an injection of a substance called hyaluronic acid, which may help lubricate the joint and reduce pain. This trial aims to see which method is more effective for patients who have had ongoing symptoms for more than three months and did not improve with other medical treatments.

To be eligible for this study, participants need to be between 18 and 45 years old and experience symptoms such as difficulty opening their mouth, pain in the jaw area, headaches, and tenderness in certain areas around the head. They must also have a specific type of jaw joint problem confirmed by an MRI. However, people who have had previous surgeries on their jaw joint, certain types of arthritis, or significant health issues will not be able to participate. If someone joins the trial, they can expect to receive one of the two treatments and be monitored for their symptoms to see how well the treatment works.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Adults with age between( 18-45) years
  • Both genders
  • The cases ciinically have either of ( limitation of mouth opening , pre-auricular pain , headache, temporal, and occipital tenderness ) and radiologically (MRI) diagnosed as ADD with reduction
  • The patients have symptom durations for more than 3 months with medical treatment.
  • Patients whom did not respond to medical treatment
  • Exclusion Criteria:
  • Previous TMJ surgery or previous arthrocentesis.
  • Patients with arthritis or history of condylar trauma
  • Patients with degenerative change of the condylar head and with facial asymmetry, retrognathism, or prognathism
  • Severe co-morbid conditions (uncontrolled diabetes, Hypertenion

About Assiut University

Assiut University, a prominent academic institution located in Egypt, is dedicated to advancing medical research and clinical trials that enhance healthcare outcomes. With a strong emphasis on innovation and collaboration, the university engages in a wide array of clinical studies across various disciplines, aiming to contribute valuable insights into disease prevention, diagnosis, and treatment. Assiut University's commitment to ethical research practices and rigorous scientific methodology ensures the integrity and reliability of its clinical trials, ultimately benefiting both the local community and the global medical landscape.

Locations

Patients applied

0 patients applied

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported