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Search / Trial NCT05968066

Practice of Fluid Therapy in Critically Ill Invasively Ventilated Patients

Launched by ACADEMISCH MEDISCH CENTRUM - UNIVERSITEIT VAN AMSTERDAM (AMC-UVA) · Jul 20, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Fluid Therapy Vasopressor Resuscitation Deresuscitation Fluids

ClinConnect Summary

This clinical trial is studying how doctors use fluid and vasopressor therapy in critically ill patients who are on invasive ventilation, which means they need a machine to help them breathe. The researchers want to understand the current practices worldwide regarding these treatments and see how they relate to patient outcomes, such as how long patients stay on the ventilator, how long they are in the hospital, and their overall survival rates.

To participate in this study, patients must be at least 16 years old, admitted to an intensive care unit, and receiving invasive ventilation for more than 24 hours. The research team will closely monitor the treatments given and the resulting health outcomes. This study is currently recruiting participants and aims to gather valuable information that could improve care for critically ill patients in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Admitted to a participating intensive care unit;
  • Receiving invasive ventilation; and
  • Duration of ventilation \> 24 hours.
  • Exclusion Criteria:
  • Age \< 16 years;
  • Patients transferred under invasive ventilation from another intensive care unit.

About Academisch Medisch Centrum Universiteit Van Amsterdam (Amc Uva)

The Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) is a leading academic medical center in the Netherlands, dedicated to advancing healthcare through innovative research, education, and patient care. Affiliated with the University of Amsterdam, AMC-UvA integrates clinical practice with cutting-edge biomedical research, fostering a multidisciplinary approach to medical challenges. The institution actively engages in clinical trials to enhance treatment options and improve patient outcomes, while promoting collaboration among healthcare professionals, researchers, and academic institutions globally. With a commitment to excellence and a focus on translational medicine, AMC-UvA plays a pivotal role in shaping the future of healthcare.

Locations

Amsterdam, Noord Holland, Netherlands

Patients applied

0 patients applied

Trial Officials

Pieter R. Tuinman, MD

Principal Investigator

Amsterdam UMC, location VUmc

Frederique Paulus, Professor

Principal Investigator

Amsterdam UMC, location AMC

Marcus J. Schultz, Professor

Principal Investigator

Mahidol Oxford Tropical Medicine Research Unit

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported