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Search / Trial NCT05968456

Complexity and Frailty in Cardiothoracic and Vascular Anesthesia (CAfCA). Prospective Multicentric Observational Study

Launched by ISTITUTO CLINICO HUMANITAS · Jul 28, 2023

Trial Information

Current as of November 08, 2025

Recruiting

Keywords

Frailty Thoracic Surgery Cardiac Surgery Vascular Surgery

ClinConnect Summary

The CAfCA trial is a study looking at how frailty, which means being more vulnerable to stress and health challenges, affects patients undergoing heart and vascular surgeries that require anesthesia. Researchers want to understand the characteristics of these patients, especially focusing on those who are frail and have other health conditions, to help predict their recovery outcomes after surgery. They have found that frailty can significantly increase risks, including the chance of complications or even death within 30 days after surgery, especially in older adults.

To participate in this study, patients must be at least 18 years old and scheduled for elective (planned) heart, thoracic, or vascular surgery. Those in urgent situations or having same-day surgeries won't be included. Participants will provide consent and can expect to share information about their health, which will help researchers gather valuable insights into how frailty and other health issues impact recovery after anesthesia and surgery. This research aims to improve care for patients in the future.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Patients scheduled for elective cardiac, thoracic or vascular surgery
  • Patients aged 18 or older
  • Patients who have provided informed consent to participate in the study.
  • Exclusion Criteria:
  • Patients subjected to surgery in urgency and emergency settings
  • Procedures in one-day surgery settings
  • Procedures without the involvement of anesthesiologists

About Istituto Clinico Humanitas

Istituto Clinico Humanitas is a leading clinical research organization based in Italy, dedicated to advancing medical science through innovative clinical trials and research initiatives. With a strong emphasis on patient-centered care and cutting-edge methodologies, the institute collaborates with various stakeholders in the healthcare sector to develop and evaluate new therapies and treatment protocols. Its multidisciplinary team of experts is committed to ensuring the highest standards of ethical practice and scientific rigor, contributing to significant advancements in medical knowledge and improved patient outcomes.

Locations

Brescia, Italy

Siena, Italy

Rozzano, Lombardia, Italy

Potenza, Italy

Pavia, Italy

Turin, Italy

Turin, Italy

Legnano, Italy

Turin, Italy

Patients applied

0 patients applied

Trial Officials

Federico Piccioni, Dr

Principal Investigator

Humanitas Research Hospital IRCCS, Rozzano-Milan

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported