Is Decreased Ovarian Reserve Related to an Increased Number of Previous Early Miscarriages?

Launched by ART FERTILITY CLINICS LLC · Jul 24, 2023

Keywords

ClinConnect Summary

This clinical trial is looking into whether a lower number of healthy eggs in the ovaries (called decreased ovarian reserve) is linked to having more early miscarriages in women. The researchers want to understand if women who have experienced multiple early miscarriages might have differences in their ovarian health compared to those who haven't. This study is currently recruiting women who have had at least one pregnancy and are being assessed at specific fertility clinics in Abu Dhabi, Al Ain, and Dubai.

To participate in this trial, women need to meet certain criteria. They should have had at least one previous pregnancy, but they cannot have certain medical conditions such as severe endometriosis, uterine abnormalities, or a history of significant ovarian surgery. Participants will have the chance to contribute to important research that could help improve understanding of infertility and miscarriage. If you or someone you know is interested in this study, please reach out to the participating clinics for more information on how to get involved.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • 1. All participants with at least 1 previous pregnancy, who are assessed in one of our clinics (ART Fertility Clinics Abu Dhabi, Al Ain, Dubai)
• Exclusion Criteria:
• • 1. Severe male factor (azoospermia, cryptozoospermia, severe oligoasthenoteratozoospermia (OAT))
• • 2. Severe Endometriosis and adenomyosis based on positive anamnesis or ultrasound performed in our center during the first consultation
• • 3. Uterine abnormalities (e.g. fibroids, different degrees of uterine septum), diagnosed by ultrasound
• • 4. History of ovarian surgery, chemotherapy, or radiation therapy
• • 5. Known genetic disorder or chromosomal abnormality
• • 6. BMI \>40Kg/m2
• • 7. Currently using hormonal contraception or hormone replacement therapy