Comparison of Live Birth Rate in Natural Cycle Single Euploid FET Versus Without Luteal Phase Support

Launched by ART FERTILITY CLINICS LLC · Jul 24, 2023

Keywords

ClinConnect Summary

This clinical trial is studying whether transferring a single healthy embryo during a natural menstrual cycle (without additional hormone support) leads to a similar chance of pregnancy as when hormone support is provided. Researchers want to find out if skipping the routine hormone treatment after the embryo transfer can still help women achieve pregnancy effectively.

To be eligible for this study, women need to be between 18 and 40 years old, have regular menstrual cycles, and must have at least one healthy embryo ready for transfer. Participants will undergo monitoring to confirm ovulation and hormone levels to ensure they are in the right stage for the procedure. If you decide to join, you will contribute to important research that may change how embryo transfers are done in the future. It's also important to know that certain medical conditions affecting the uterus or ovaries may prevent you from participating in this study.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • Age: 18 to 40 years
• • Regular ovulatory cycles
• • Availability of at least one euploid embryo after Trophectoderm biopsy for PGT-A on day 5 or day 6
• • Detection of ovulation by P4 rise \> 1.0 ng/ml after LH surge
• • P4 value of at least 5 ng/ml on day 4 after ovulation
• Exclusion Criteria:
• • History of repeated pre-menstrual spotting
• • Factors affecting the implantation through anatomical changes of the uterus / ovaries or the tubes (adenomyosis, Asherman syndrome, endometriosis, uterine fibroids / polyps, isthmocele with intracavitary fluid presence, hydrosalpinx....)