Comparison of Bladder Pressure Versus Regional Intestinal Tissue Oxygenation in Infants

Launched by UNIVERSITY CHILDREN'S HOSPITAL, ZURICH · Jul 24, 2023

Keywords

ClinConnect Summary

This clinical trial is designed to compare two ways of measuring pressure and oxygen levels in the intestines of infants who are undergoing specific surgeries. The researchers want to find out if measuring oxygen levels in the intestines using a special light technology (called near-infrared spectroscopy) is more reliable than measuring pressure in the bladder. This study will involve infants who are less than 12 months old and are prepared for certain types of surgeries, such as laparoscopic pyeloplasty or other related procedures.

If your child is eligible and participates in the trial, they will have their bladder pressure and intestinal oxygen levels measured once during surgery and once after. The trial is currently recruiting infants, and the goal is to gather important information that could help improve care for babies with abdominal issues. Eligibility criteria include being under 12 months old, having a legal guardian who can give consent, and meeting specific health requirements. This study is a step towards better understanding how to monitor and treat abdominal conditions in young children.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Prepped and consented for laparoscopic pyeloplasty or minimal PSARP with perineal or vestibular fistula or lateral thoracotomy for the correction of esophageal atresia
• • Age of 12 months old or less at operation
• • Legal custodian gives consent
• Exclusion Criteria:
• • Anterior abdominal wall thickness greater than 12 mm measured on preoperative MRI imaging if available
• • Patients planned for additional intestinal surgeries or non-standard pyeloplasty, e.g. pyeloplasty with nephrostoma
• • Patients planned for laparoscopic pyeloplasty whose intraoperative urine sample shows pathological results
• • Patients with esophageal atresia who experience pulmonary decompensation and need urgent surgery for fistula clipping