The Molecular Basis of Inherited Reproductive Disorders

Launched by STEPHANIE B. SEMINARA, MD · Jul 31, 2023

Keywords

ClinConnect Summary

This clinical trial is focused on understanding the genes that play a role in puberty and reproduction in humans. Researchers want to learn more about conditions like hypogonadotropic hypogonadism, Kallmann syndrome, and delayed puberty, which can affect how the body develops and functions in terms of reproduction. By studying these conditions, scientists hope to uncover important information that could help improve diagnosis and treatment in the future.

The trial is currently looking for participants of all genders who are experiencing certain reproductive issues. This includes individuals who have not gone through puberty at the right age, those who have started puberty too early, or those who have low hormone levels after normal puberty. Additionally, family members of affected individuals are also encouraged to join the study. Participants can expect to contribute to valuable research that may lead to better understanding and support for reproductive health issues. Your participation could make a difference in the lives of many others facing similar challenges.

Gender

ALL

Eligibility criteria

• Participants must belong to one of the following categories:
• • Failure to go through a normal, age-appropriate, spontaneous puberty and low sex steroid levels in the setting of low/normal gonadotropins or,
• • Abnormally early development of puberty or,
• • Normal puberty with subsequent development of low gonadotropin levels or,
• • Evidence of a reproductive disorder with high gonadotropin levels or,
• • Pre-pubertal individuals with features suggestive of hypogonadotropic hypogonadism or,
• • Affected and unaffected family members of individuals that fit criteria above