COAgulation Disorders in Ischaemic and Haemorrhagic Stroke

Launched by ZIEKENHUIS OOST-LIMBURG · Jul 25, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how blood clotting and inflammation affect patients who have experienced different types of strokes, including ischemic stroke (caused by a blocked blood vessel), hemorrhagic stroke (caused by bleeding in the brain), and aneurysmal subarachnoid hemorrhage (bleeding around the brain due to a burst aneurysm). The researchers want to learn more about the body's clotting systems and how they relate to brain damage. By measuring specific markers in the blood, they hope to predict how well patients will recover in the months following their stroke.

To participate in this study, individuals must be hospitalized with one of the types of strokes mentioned. Specifically, they are looking for patients aged 65 and older who are experiencing a stroke that is not caused by trauma. Patients who refuse to participate, have certain types of bleeding due to injury, or are on medications that affect blood clotting before their first blood sample will not be included. Participants can expect to provide blood samples for testing, which will help researchers better understand stroke impacts and potentially lead to improved treatment strategies in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Presenting at the hospital with ischaemic stroke, haemorrhagic stroke, aneurysmal subarachnoid haemorrhage or any other type of non-traumatic, intracranial bleeding
• • In patients with minor ischemic stroke (NIHSS \<= 4) only baseline lab sampling will be performed (T0 and T0B).
• Exclusion Criteria:
• • Refusal of participation by patient or legal representative
• • Traumatic intracranial (subdural, subarachnoid, epidural haematoma) bleeding
• • Patients receiving treatment with interference on coagulation (pro / anti) before first sampling: in this group of patients the coagulation assessment at presentation will be excluded, further lab sampling is performed according to protocol.
• • Patients categorized as having stroke mimic will be excluded from analysis afterwards