Investigation of the Use of a Probiotic Supplement in People With Long COVID
Launched by SHEFFIELD HALLAM UNIVERSITY · Aug 2, 2023
Trial Information
Current as of September 30, 2025
Unknown status
Keywords
ClinConnect Summary
This clinical trial is investigating whether a probiotic supplement can help improve symptoms in people suffering from Long COVID. Long COVID refers to ongoing health issues that some individuals experience for at least 12 weeks after having COVID-19. The study is currently looking for participants aged 65 to 74 years who fit the criteria for Long COVID, meaning they have persistent symptoms after their COVID-19 infection. However, individuals with serious health conditions, such as heart disease or cancer, will not be eligible to join.
If you decide to participate, you will be part of a double-blinded randomized trial, meaning neither you nor the researchers will know who is receiving the probiotic and who is receiving a placebo (a non-active treatment). This approach helps ensure that the results are fair and reliable. Participants can expect regular check-ins and assessments to monitor any changes in their symptoms throughout the study. Overall, this trial aims to determine if probiotics can provide relief for those experiencing the lingering effects of COVID-19.
Gender
ALL
Eligibility criteria
- • Inclusion Criteria: Long COVID defined as National Institute for Health and Care Excellence (NICE) criteria for Long COVID (Persistent symptoms at least 12 weeks after a confirmed or suspected Covid-19 infection).
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- • Exclusion Criteria: Significant co-morbidities - no pre-existing diagnosis of hypertension, diabetes, cerebrovascular, cardiovascular or peripheral vascular disease, coagulopathy or haematological disorder or current or recent cancer.
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About Sheffield Hallam University
Sheffield Hallam University is a leading institution in the United Kingdom, recognized for its commitment to advancing research and innovation in the health sciences. With a strong emphasis on interdisciplinary collaboration, the university conducts rigorous clinical trials aimed at improving patient outcomes and enhancing healthcare practices. Its research teams are composed of experienced professionals dedicated to ethical standards and scientific integrity, ensuring that trials not only contribute to academic knowledge but also address real-world health challenges. Through its state-of-the-art facilities and partnerships with healthcare organizations, Sheffield Hallam University strives to translate research findings into practical applications that benefit communities and inform clinical practices.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Sheffield, United Kingdom
Patients applied
Trial Officials
Caroline Dalton, PhD
Principal Investigator
Sheffield Hallam University
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported