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Search / Trial NCT05975567

Deploying Novel Imaging Modalities Towards a Three-dimensional (3D) CARDIOvascular PATHology

Launched by ARISTOTLE UNIVERSITY OF THESSALONIKI · Aug 2, 2023

Trial Information

Current as of July 01, 2025

Not yet recruiting

Keywords

Micro Ct Light Sheet Fluorescence Microscopy Intravascular Ultrasound Optical Coherence Tomography 3 D Cardiovascular Imaging 3 D Cardiovascular Pathology

ClinConnect Summary

The 3D-CARDIOPATH study is a clinical trial aimed at exploring new 3D imaging techniques to better understand heart diseases, particularly conditions like coronary artery disease and aortic valve problems. Researchers will examine heart tissues from patients who have experienced sudden cardiac death or had a heart attack, along with aortic valves that have been surgically removed. They will use advanced imaging methods to create detailed 3D pictures of these tissues, which will help improve diagnosis and treatment options for cardiovascular diseases.

To participate, individuals must be over 18 years old and meet certain criteria, such as having experienced sudden cardiac death or being treated for a heart attack. Participants can expect their heart tissues to be scanned using advanced imaging technologies, and their medical history will be recorded to understand better how these conditions affect patients. It's important to note that the trial is not yet recruiting participants, and those with severe mental health issues or who pass away shortly after surgery will not be eligible to join.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Age \>18 years.
  • Patients with sudden cardiac death for coronary artery imaging.
  • Patients with STEMI undergoing PCI and thrombus aspiration for thrombus imaging.
  • Patients with CAVD undergoing cardiac replacement of calcific aortic valve for valve imaging.
  • Exclusion Criteria:
  • Patients dying after the execution of their cardiac surgery.
  • Patients with altered mental status; unable or unwilling to provide informed consent for specimen imaging and clinical follow-up.

About Aristotle University Of Thessaloniki

Aristotle University of Thessaloniki (AUTH) is a prestigious institution in Greece, renowned for its commitment to advancing knowledge and innovation in the field of clinical research. As a leading academic sponsor of clinical trials, AUTH leverages its extensive resources and expertise to conduct rigorous studies that contribute to the understanding of various medical conditions and the development of novel therapeutic interventions. The university fosters collaboration among multidisciplinary teams, ensuring adherence to the highest ethical standards and regulatory requirements while promoting scientific excellence and enhancing patient care.

Locations

Patients applied

0 patients applied

Trial Officials

Georgios I Tagarakis, MD, PhD

Principal Investigator

Cardiothoracic Surgery Department, Aristotle University of Thessaloniki

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported