Circadian Rhythm and Other Factors in Memory Clinic Patients

Launched by ASSISTANCE PUBLIQUE - HÔPITAUX DE PARIS · Aug 3, 2023

Keywords

ClinConnect Summary

The CIRCAME study is a research trial taking place in two memory clinics in Paris. Its main goal is to understand how daily rhythms (like sleep and wake times) and other personal factors might be linked to different types and stages of dementia, such as Alzheimer’s disease and frontotemporal dementia. Researchers want to see if these factors can help doctors identify dementia early, even before more common indicators are considered. They are also looking into how these factors might predict how quickly a person’s memory and daily activities may decline over time.

To participate in this study, you need to be at least 18 years old, able to provide consent, and be enrolled in the French social security system. However, individuals with certain skin allergies, severe psychiatric disorders, or those who need assistance due to significant cognitive impairment may not be eligible. If you join the study, you can expect to wear a small device that tracks your daily movements for nine days. This research could provide valuable insights into dementia and improve how it is diagnosed and treated in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patient of legal age (18 or over)
• • Signed informed consent form
• • Patient affiliated to the french social security system
• Exclusion Criteria:
• • Skin allergy to plastic
• • Diagnosis of psychiatric disorder that can explain all cognitive symptoms
• • Inability to come accompanied for patients with a Mini-Mental State Examination (MMSE) cognitive score ≤18 or a clinician assessment indicating the need to be accompanied (e.g. wheelchair use, agitation)
• • Participation at the time of inclusion and during the 9-day period of wearing the accelerometer in interventional research with potential impact on circadian rhythm