PROPEL-2: Prophylactic Negative Pressure Wound Therapy in Laparotomy Wounds
Launched by ROYAL COLLEGE OF SURGEONS, IRELAND · Aug 3, 2023
Trial Information
Current as of July 24, 2025
Recruiting
Keywords
ClinConnect Summary
The PROPEL-2 clinical trial is exploring whether a special type of dressing called Negative Pressure Wound Therapy (NPWT) can help patients who have had surgery on their abdomen. This dressing is designed to help prevent infections, reduce complications after surgery, and improve the appearance of scars compared to regular dressings. If you or a loved one are 18 years or older and will be having visceral abdominal surgery through a midline incision, you might be eligible to participate in this trial.
Participants in the trial will be asked to complete some questionnaires about their recovery and wound healing. It’s important to note that individuals who cannot follow the study’s guidelines may not be eligible. The study is actively recruiting participants, and anyone involved can expect close monitoring of their recovery process to see how well the NPWT dressing works compared to standard options.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Aged 18 years or older
- • Patient requires visceral abdominal surgery via a midline laparotomy
- • Patients who can complete questionnaires
- Exclusion Criteria:
- • • Patients who are unable to adhere to protocol requirements
About Royal College Of Surgeons, Ireland
The Royal College of Surgeons in Ireland (RCSI) is a prestigious educational and research institution dedicated to advancing surgical practice and healthcare through innovative research, education, and clinical excellence. As a clinical trial sponsor, RCSI plays a pivotal role in conducting cutting-edge research that aims to improve surgical outcomes and patient care. With a commitment to fostering collaboration among healthcare professionals, researchers, and industry partners, RCSI is at the forefront of developing evidence-based interventions and therapies that address critical health challenges. Through its rigorous scientific approach and adherence to ethical standards, RCSI strives to contribute significantly to the advancement of medical knowledge and the enhancement of surgical practices globally.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Dublin, , Ireland
Galway, , Ireland
Dublin, , Ireland
Dublin, , Ireland
Limerick, , Ireland
Dublin, , Ireland
Letterkenny, , Ireland
Waterford, , Ireland
Sligo, , Ireland
Ballinasloe, , Ireland
Castlebar, , Ireland
Drogheda, , Ireland
Tralee, , Ireland
Patients applied
Trial Officials
Claire Donohoe, PhD, FRCSI
Principal Investigator
Trinity College Dublin /Royal College of Surgeons
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported