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Search / Trial NCT05978687

The Use of Lidocaine Gel Versus Subconjunctival Xylocaine Injection in Pterygium Excision

Launched by VRIJE UNIVERSITEIT BRUSSEL · Jul 30, 2023

Trial Information

Current as of June 26, 2025

Recruiting

Keywords

Lidocaine Gel Pterygium Dryness Irritation

ClinConnect Summary

This clinical trial is studying two different ways to numb the eye during pterygium surgery, which is a procedure to remove a growth on the eye's surface. The researchers want to compare the use of a gel called lidocaine with a traditional method that involves an injection of a numbing medicine called xylocaine. They believe that the gel might be less painful and provide better comfort during the surgery, while also helping to keep the eye surface moist and less dry afterwards.

To participate in this trial, you need to be someone who requires pterygium excision surgery and is between the ages of 18 and 75. However, if you have certain health conditions like autoimmune diseases or have had prior pterygium surgery, you may not be eligible. If you join the trial, you can expect to share your experience of pain during and after the surgery, as well as any dryness in your eyes. This study aims to help improve comfort for future patients undergoing this type of eye surgery.

Gender

ALL

Eligibility criteria

  • Inclusion Criteria:
  • Indication of pterygium excision
  • Exclusion Criteria:
  • No history of auto-immune diseases such as Sjögren, Lupus, Graves, Graft-versus-host disease, rheumatoid artritis
  • No history of deafness, anxiety disorders, communicative barrier, impossibility to comprehend the Visual Analogue Pain Scale or the OSDI questionnaire.
  • Patient who already had pterygium excision

About Vrije Universiteit Brussel

The Vrije Universiteit Brussel (VUB) is a distinguished research university located in Brussels, Belgium, known for its commitment to innovative education and cutting-edge research across various disciplines. As a clinical trial sponsor, VUB actively engages in advancing medical knowledge and improving patient care through rigorous scientific investigations. The university fosters collaborations with healthcare institutions and industry partners, ensuring that its clinical trials adhere to the highest ethical standards and regulatory requirements. VUB's research initiatives are driven by a multidisciplinary approach, leveraging expertise from fields such as medicine, health sciences, and biomedical engineering to address pressing health challenges and contribute to the development of novel therapies.

Locations

Brussel, , Belgium

Brussel, Brussels, Belgium

Patients applied

0 patients applied

Trial Officials

Karolien Termote, Master

Principal Investigator

Vrije Universiteit Brussel

Timeline

First submit

Trial launched

Trial updated

Estimated completion

Not reported