Clinical Study on Endoscopic Management of GOV1 Esophagogastric Varices

Launched by SECOND AFFILIATED HOSPITAL, SCHOOL OF MEDICINE, ZHEJIANG UNIVERSITY · Jul 31, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to treat patients with GOV1 esophageal and gastric varices, which are swollen veins in the esophagus and stomach that can cause serious health issues. The study will involve injecting a special gel into the gastric varices while also treating the esophageal varices using methods like ligation (tying off the veins) or sclerotherapy (injecting a solution to shrink the veins). The goal is to improve treatment effectiveness, reduce the chances of these varices coming back, lower the risk of death, shorten hospital stays, and cut down on treatment costs.

To participate in this trial, you need to be at least 18 years old and have been diagnosed with GOV1 esophageal and gastric varices through a CT scan. However, if you have liver cancer, severe heart or lung problems, advanced liver disease, or have had previous treatments for bleeding caused by high blood pressure in the portal vein, you won't be eligible. The trial is not yet recruiting participants, but if you qualify, you can expect a carefully monitored treatment approach aimed at improving your health and reducing complications related to varices.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • GOV1 esophageal and gastric varices identified by CT; more than 18 years old;
• Exclusion Criteria:
• • Complicated with liver cancer, severe cardiopulmonary insufficiency, stage III and above hepatic encephalopathy, severe natural portal shunt formation, and previous treatment of portal hypertensive bleeding (including endoscopic, interventional, and surgical procedures).