Efficacy of Intra-articular Hyaluronate Injection for Adhesive Capsulitis

Launched by TRI-SERVICE GENERAL HOSPITAL · Aug 1, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the effectiveness of a treatment called hyaluronic acid (HA) injections for people with adhesive capsulitis, commonly known as frozen shoulder. Adhesive capsulitis is a condition where the shoulder becomes stiff and painful, making it hard to move. In this trial, 30 patients diagnosed with frozen shoulder will receive HA injections directly into their shoulder joint once a week for three weeks. Researchers will then measure how much the patients can move their shoulder and how much pain they feel at several points after treatment.

To be eligible for this trial, participants should be between 40 and 70 years old and have a specific type of frozen shoulder that shows limited movement compared to their healthy shoulder. They should also not have certain serious shoulder issues, like a torn rotator cuff or recent shoulder surgery. If you or a loved one is experiencing shoulder stiffness and pain, this trial may offer a potential treatment option, and participants will be closely monitored throughout the study to ensure their safety and gather valuable information about the treatment's effectiveness.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • A. Patients diagnosed with frozen shoulder by a clinical physician based on the patient's medical history, physical examination, X-ray, and ultrasound or magnetic resonance imaging reports.
• • B. Clinical course: Patients must have a pain score of less than 3, no nighttime shoulder pain, and be in the post-freezing stage, primarily presenting restricted shoulder joint range of motion.
• • C. The affected shoulder joint must have at least two angles of shoulder joint movement reduced by at least 30% compared to the healthy side: shoulder flexion, abduction, and external rotation, or a single affected side abduction angle reduced by 50% relative to the healthy side.
• • D. Age between 40 to 70 years old.
• • -
• Exclusion Criteria:
• • A. full-thickness tear or massive tear of the rotator cuff tendons or calcific tendinitis.
• • B. Presence of systemic rheumatic disease. C. History of shoulder fracture or previous shoulder surgery. D. Received shoulder injections for treatment within the last 3 months. E. Acute cervical nerve root compression. F. Current pregnancy or lactation. G. Patients with shoulder instability or cancer. H. Patients with cognitive impairment, unable to follow simple instructions, or unable to comply with the study procedures.