Menopause Related Influences on Leukocyte Distribution, Monocyte Function and Platelet Reactivity

Launched by HEINRICH-HEINE UNIVERSITY, DUESSELDORF · Aug 2, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at how menopause affects certain blood components that can influence heart health. Researchers want to understand how menopause changes the way white blood cells and platelets (a type of blood cell that helps with clotting) behave, especially in relation to conditions like arteriosclerosis (hardening of the arteries) and heart attacks. Before menopause, women generally experience fewer heart problems than men, but this trend seems to change after menopause, possibly due to the loss of the protective effects of estrogen, a hormone that helps keep blood vessels healthy.

To be eligible for this study, participants should be 18 years or older and currently receiving treatment in the cardiology department. Both men and women are welcome, as long as they can understand and follow the study instructions and provide written consent. Participants will undergo various assessments related to their blood and cardiovascular health. It’s important for potential participants to know that those with bleeding disorders or under 18 cannot take part in the study. The goal is to gather valuable information that could lead to better heart health strategies for all individuals, especially postmenopausal women.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age \> 18 years
• • Male, female, diverse patients with current treatment in the Department of Cardiology, Pneumology and Angiology.
• • Persons who are able to understand and follow the instructions of the study staff
• • Written informed consent
• Exclusion Criteria:
• • Age \< 18 years
• • Lack of written consent to participate in the study
• • coagulation disorders