Towards Improved Diagnostics for Suspected Platelet Function Disorders

Launched by REGION STOCKHOLM · Aug 9, 2023

Keywords

ClinConnect Summary

This clinical trial is focused on improving tests that check how well platelets, the tiny cells in our blood that help stop bleeding, are functioning. Researchers want to see if new tests can better identify patients who have problems with their platelets, known as platelet function disorders. The study is taking place at two hospitals in Sweden, where patients with either confirmed or suspected platelet issues will be recruited to participate.

To be eligible for the trial, participants need to have a known platelet function disorder or show signs that they might have one, such as unusual results from initial screening tests. However, people who are currently taking certain blood-thinning medications or have specific blood conditions will not be included. If you or a loved one are considering joining, you can expect to undergo some new tests that aim to provide clearer insights into platelet function, which could lead to better diagnosis and treatment in the future. The trial is currently recruiting participants of all ages.

Gender

ALL

Eligibility criteria

• Inclusion Criteria, known defects:
• • Known platelet function disorder under follow-up at Karolinska University Hospital (genetic or functional assay)
• • High likelihood of platelet function disorder (aberrant screening test with inheritance)
• • Family investigation for platelet disorder
• Exclusion Criteria, known defects::
• • Antiplatelet or anticoagulant drugs
• • vWF:GPIb below 0.40 IU/mL
• • Hematocrit below 0.35 or above 0.50
• • Other coagulation disorder
• Inclusion Criteria, suspected platelet function disorder:
• • Bleeding investigation at Karolinska University Hospital
• Exclusion Criteria, suspected platelet function disorder::
• • Antiplatelet or anticoagulant drugs
• • vWF:GPIb below 0.40 IU/mL
• • Hematocrit below 0.35 or above 0.50
• • Other coagulation disorder