Bone Marrow Aspirate Concentrate (BMAC) vs Corticosteroid Injection

Launched by RUSH UNIVERSITY MEDICAL CENTER · Aug 2, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the effects of a treatment called Bone Marrow Aspirate Concentrate (BMAC) compared to a corticosteroid injection for people suffering from knee osteoarthritis. Osteoarthritis is a common condition that causes pain and stiffness in the joints, and the trial aims to see which treatment provides better relief based on what patients report about their pain and function.

To participate in this study, individuals need to be between the ages of 18 and 70 and have had knee pain from osteoarthritis that hasn't improved with other treatments for at least six weeks. They should also have a moderate level of pain, scoring at least a 4 out of 10 on a pain scale. Participants will receive either the BMAC treatment or the corticosteroid injection, and their progress will be monitored over time. It’s important to note that certain health conditions, such as diabetes or recent knee injections, may prevent someone from joining the trial. If you or someone you know fits the criteria and is dealing with knee pain, this trial could be a chance to explore a new treatment option.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Patients between the ages of 18-70
• • Long standing knee pain from osteoarthritis (KL grade 2-3) despite conventional treatments such as activity modification, weight loss, physical therapy, analgesics, nonsteroidal anti-inflammatory drugs, or injection therapy for at least 6 weeks
• • 7-day average pain score of at least 4 on VAS scale
• Exclusion Criteria:
• • Systemic diseases (Diabetes, malignancies, infections, etc.)
• • Post-traumatic arthritis
• • Patient had intra-articular injection on affected knee in last three months