Fusion Status After ACDF
Launched by ROTHMAN INSTITUTE ORTHOPAEDICS · Aug 9, 2023
Trial Information
Current as of June 26, 2025
Enrolling by invitation
Keywords
ClinConnect Summary
Pseudarthrosis, a failure of bony fusion, is one of the most common causes of revision surgery following anterior cervical discectomy and fusion (ACDF). The interbody spacer is an important component of bony fusion in ACDF, and we aim to compare machined allograft spacers versus iliac crest allograft in a randomized controlled trial. We hypothesize that iliac crest allograft will improve anterior cervical discectomy and fusion arthrodesis rates and diminish the amount of intervertebral graft resorption when compared to off-the-shelf machined allografts
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • patients 18 years of age or older
- • preoperative diagnosis of cervical radiculopathy and/or cervical myelopathy.
- Exclusion Criteria:
- • patients undergoing a revision cervical procedure
- • current smokers
- • patient with surgical indications of tumor, infection, or trauma
About Rothman Institute Orthopaedics
Rothman Institute Orthopaedics is a leading healthcare organization specializing in orthopedic care and research. With a commitment to advancing the field of orthopedics, Rothman Institute conducts innovative clinical trials aimed at improving patient outcomes and enhancing treatment methodologies. Renowned for its team of highly skilled orthopedic surgeons and researchers, the institute integrates cutting-edge technology and evidence-based practices to deliver exceptional care. Through its rigorous research initiatives, Rothman Institute is dedicated to fostering advancements in orthopedic medicine and contributing to the overall improvement of musculoskeletal health.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Philadelphia, Pennsylvania, United States
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported