NIA_Improving Function and Well-being by Improving Patient Memory: Transdiagnostic Sleep and Circadian Treatment

Launched by UNIVERSITY OF CALIFORNIA, BERKELEY · Aug 2, 2023

Keywords

ClinConnect Summary

The clinical trial titled "Improving Function and Well-being by Improving Patient Memory" is studying a new approach to help improve sleep and memory in individuals aged 50 and older who face challenges related to sleep disorders and memory issues. The researchers want to see if a special program called the Memory Support Intervention (MSI) can enhance sleep quality, support daily functioning, and boost memory skills. They are currently looking for participants who are 50 years or older, speak English, and have mobility difficulties, low income, and sleep problems, as determined by specific survey questions.

If you or a loved one qualify and decide to participate, you can expect to engage in an open trial where the effectiveness of this memory support program will be evaluated. However, certain conditions may exclude individuals from joining, such as severe untreated sleep issues or medical conditions that would make it hard to follow the treatment plan. This trial aims to provide better support for those struggling with sleep and memory, potentially leading to improved quality of life.

Gender

ALL

Eligibility criteria

• Inclusion criteria:
• • 1. Aged 50 years and older;
• • 2. English language fluency;
• • 3. Experiencing a mobility impairment;
• • 4. Low income;
• • 5. Exhibit a sleep or circadian disturbance as determined by endorsing 4 "quite a bit" or 5 "very much" (or the equivalent for reverse scored items) on one or more PROMIS-SD questions.
• • 6. 25-30 on the Montreal Cognitive Assessment, as a negative screen for cognitive impairment.
• • 7. Able/willing to give informed consent.
• Exclusion criteria:
• • 1. Severe untreated sleep disordered breathing (AHI\>30) or moderate untreated sleep disordered breathing with severe daytime sleepiness (AHI of 15-30 and Epworth Sleepiness Scale \>10);
• • 2. Medical conditions that prevent a participant from comprehending and following the basic tenants of treatment (e.g., dementia) or that interfere with sleep in a manner that can't be addressed by a cognitive behavioral treatment (e.g., the Structured Clinical Interview for Sleep Disorders will be used to screen for narcolepsy, REM sleep behavior disorder) or that may preclude full participation (e.g., receipt of end of life care);
• • 3. Homelessness;
• • 4. Night shift work \>2 nights per week in the past 3 months;
• • 5. Substance abuse/dependence only if it makes participation in the study unfeasible;
• • 6. Suicide risk sufficient to preclude treatment on an outpatient basis.