The Alkmaar MLPTI Cohort Study: Outcomes at 9 Years

Launched by NOORDWEST ZIEKENHUISGROEP · Aug 6, 2023

Keywords

ClinConnect Summary

SUMMARY Rationale: Recent studies indicate that moderate and late preterm infants (MLPTI, gestational age (GA) 32-36 weeks) are at risk of lower IQ scores, behavioural and attention problems and academic underachievement at the age of 6 to 10 years. These recent findings of impaired outcomes above the age of 6 contrast with earlier studies that suggested that outcomes of MLPTI are comparable to those of full-term children. However, since the number of studies performed on MLPTI above 6 years of age is limited and show different results, the developmental outcomes of MLPTI remains a subject ...

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• In order to be eligible to participate in this study, a subject must meet all the following criteria:
• • The participant is born in or transferred to the NWZ Alkmaar between January 1st, 2014 and April 18th, 2016 (the time in which the participants of trial NL50800.094.14 were born).
• • The participant born at a gestational age from 32 to 35+6 weeks.
• • Both parents of the participant have given informed consent to participate in the 9 years trial
• In order to be eligible to participate in the control group of this study, a subject must meet all the following criteria:
• • The participant is 9 years old when participating in this study and is a friend or classmate of the included MLPTI.
• • Both parents of the participant have given informed consent for the participation of the study.
• Exclusion Criteria:
• A potential subject who meets any of the following criteria will be excluded from participation in this study:
• • The participant's parents are not able to fill out questionnaires or perform tests in Dutch.
• • The participant has a severe developmental or genetic disorder and is thereby not able to perform the tests.
• • The participant is not able to come to the outpatient clinic to do the tests.
• A potential subject who meets any of the following criteria will be excluded from participation in this study as part of the control group:
• • The participant is born with a GA \< 37 weeks.
• • The participant has a severe developmental or genetic disorder and is thereby not able to perform the tests.
• • The participant had complications after birth (e.g. admission at a Neonatal ward)
• • The participant needs special education