Effects of Modified Fixed Twin Block Versus Removable Twin Block on Skeletal Class 2 Growing Patients With Mandibular Deficiency
Launched by CAIRO UNIVERSITY · Aug 13, 2023
Trial Information
Current as of July 09, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the effects of two types of orthodontic devices—modified fixed twin blocks and removable twin blocks—on young patients who have a specific dental condition called skeletal Class 2 malocclusion. This condition means that the upper jaw is positioned too far forward compared to the lower jaw, which can lead to bite problems. The trial is currently recruiting female patients aged between 3 and 5 years who show signs of growth and have a noticeable overbite (where the upper teeth significantly overlap the lower teeth).
If you or your child are eligible to participate, you can expect to receive one of the two treatments and be monitored to see how well each option works in correcting the malocclusion. It's important to note that patients who have already had certain types of dental treatment, are older than 15 years, or have specific dental conditions are not eligible for this study. This research could help improve orthodontic treatments for children with similar conditions in the future.
Gender
FEMALE
Eligibility criteria
- Inclusion Criteria:
- • Skeletal Class 2 malocclusion cases (ANB ≥ 5 degrees)
- • Overjet ≥ 5 mm
- • Growing patients (CVMS 3 or 4)
- Exclusion Criteria:
- • Skeletally mature patients 15 years old or above
- • Patients with normal mandible and only protruded upper incisors.
- • Syndromic, cleft patients and patients with dental anomalies
- • Previous orthopaedic or orthodontic treatment
- • No sex predilection.
About Cairo University
Cairo University, a premier institution in Egypt, is dedicated to advancing medical research and education through innovative clinical trials. With a strong emphasis on improving healthcare outcomes, the university collaborates with various stakeholders to conduct rigorous scientific studies that address critical health challenges. Leveraging its extensive resources and expert faculty, Cairo University aims to contribute valuable insights to the medical community and enhance patient care both locally and globally. Through its commitment to ethical research practices and excellence, the university plays a pivotal role in shaping the future of healthcare in the region.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Cairo, , Egypt
Patients applied
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported