Objective Concussion Assessment Using MRI and Metabolomics

Launched by ST. JOSEPH'S HEALTHCARE HAMILTON · Aug 12, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how concussions, also known as mild traumatic brain injuries (mTBI), affect the brain over time. Researchers are using advanced MRI scans to look for changes in the brain and to compare these changes with the symptoms people experience after a concussion, like headaches and trouble concentrating. By understanding this relationship better, the study aims to improve how concussions are diagnosed and managed.

To participate in this trial, you need to be between the ages of 9 and 50 and have had a concussion within the last two weeks. Unfortunately, if you are younger than 9 or older than 50, or if you have certain medical conditions or devices that might make an MRI unsafe, you won't be eligible. Participants will undergo MRI scans and provide information about their symptoms, helping researchers gain important insights into brain injuries. If you're interested, this study is currently recruiting participants of all genders.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Aged between 9-50
• • Recently sustained a concussion (within the last 2 weeks)
• Exclusion Criteria:
• • Aged 8 and younger or 51 and older
• • Unable to provide consent (e.g., poor English language skills, etc.)
• • History of liver or kidney disease
• * MRI contraindications:
• • Pacemaker
• • Stent
• • Joint prothesis
• • Implanted devices
• • Claustrophobia
• • Pregnant
• • Permanent piercings
• • Chronic/abusive use of alcohol and/or illicit drugs
• • Previous stroke or moderate/severe traumatic brain injury, subarachnoid hemorrhage, or intracranial hemorrhage
• • Healthy control participants must not have a concussion history or recently sustained a concussion