PET/CT* vs. Cardiac CT for Detecting Coronary Atherosclerotic Disease [*PET: Positron Emission Tomography; CT: Computed Tomography]

Launched by JOHNS HOPKINS UNIVERSITY · Aug 8, 2023

Keywords

ClinConnect Summary

This clinical trial is comparing two types of imaging tests—PET/CT and cardiac CT—to see which one better detects coronary atherosclerotic disease, a condition where plaque builds up in the arteries of the heart. Early detection is important because it helps doctors take steps to prevent serious heart problems. The study will involve 33 patients who are experiencing symptoms that suggest they might have coronary artery disease (CAD) and have been referred for cardiac CT testing.

To participate in this study, you need to be at least 18 years old and have stable symptoms that make your doctor suspect you might have coronary heart disease. However, if you have a history of heart disease, are pregnant, have certain heart conditions like atrial fibrillation, are significantly overweight, or have other serious health issues, you would not be eligible. Participants will undergo imaging tests and will help researchers understand which method is more effective for detecting heart disease, which could lead to better care in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Male or female patients
• • 18 years or older
• • referred for coronary CT angiography because of suspected coronary heart disease (CHD) with stable symptoms
• Exclusion Criteria:
• • The patient has a history of coronary heart disease, defined by prior myocardial infarction or prior coronary artery revascularization.
• • Pregnancy.
• • Atrial fibrillation.
• • Morbid obesity defines as a body mass index of \>40.
• • The patient has any other clinically significant medical condition that in the opinion of the Investigator could impact the patient's ability to successfully complete the trial.