Collection of Samples From Subjects With Various Skin Conditions and Healthy Volunteers

Launched by INNOVADERM RESEARCH INC. · Aug 9, 2023

Keywords

ClinConnect Summary

This clinical trial is focused on gathering samples from people with various skin conditions, such as acne, atopic dermatitis (eczema), chronic hand eczema, hidradenitis suppurativa, plaque psoriasis, and palmoplantar pustulosis. The goal is to better understand these inflammatory skin diseases at a molecular level, which means looking closely at the biological processes involved. The study is currently recruiting participants, including healthy volunteers and individuals with the specified skin conditions, who are between the ages of 18 and 45 (for acne) or 18 and older (for other conditions).

To participate, individuals need to be in good health and able to provide consent. They must also commit to following the study procedures and be available for the study's duration. Participants will have their skin conditions assessed, and samples collected, which may help improve future treatments for these conditions. It’s important to note that pregnant women and those with certain skin diseases that could affect the study's results cannot participate. This trial offers an opportunity to contribute to important research that may lead to better care for skin health.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• All subjects:
• • 1. Subject is willing to participate and is capable of giving informed consent. Note: Consent must be obtained prior to any study-related procedures.
• • 2. Subject must be willing to comply with all study procedures and must be available for the duration of the study.
• Healthy volunteers:
• • 3. Male or female subject aged 18 years or older, at the time of consent.
• • 4. Subject is in good general health, according to the investigator's judgment.
• Subjects with Acne:
• • 5. Male or female subject aged 18 to 45 years old, inclusive, at the time of consent.
• Subjects with AD:
• • 6. Male or female subject aged 18 years or older, at the time of consent.
• • 7. Subject has clinically confirmed diagnosis of active AD, according to Hanifin and Rajka criteria.
• Subjects with CHE:
• • 8. Male or female subject aged 18 years or older, at the time of consent.
• • 9. Subject has at least a 6-month history of CHE before Screening (information obtained from medical chart or subject's physician, or directly from the subject).
• Subjects with HS:
• • 10. Male or female subject aged 18 years or older, at the time of consent.
• • 11. Subject has a clinically confirmed diagnosis of active HS with a disease duration of ≥ 6 months before screening as determined by the investigator through subject interview and/or review of the medical history.
• Subjects with PPP:
• • 12. Male or female subject aged 18 years or older at the time of consent.
• • 13. Subject has at least a 6-month history of PPP as defined by the presence of pustules on palms and/or soles, but without evidence of infection on palms and soles (information obtained from medical chart or subject's physician, or directly from the subject).
• Subjects with psoriasis:
• • 14. Male or female subject aged 18 years or older, at the time of consent.
• Exclusion Criteria:
• All subjects:
• • 1. Subject is a female who is pregnant or who is planning to become pregnant during the study.
• • 2. Subject has a history of skin disease or presence of skin condition that, in the opinion of the investigator, would interfere with the study assessments.