Unraveling the Klinefelter's Disease Physiopathology

Launched by CLINIQUES UNIVERSITAIRES SAINT-LUC- UNIVERSITÉ CATHOLIQUE DE LOUVAIN · Aug 11, 2023

Keywords

ClinConnect Summary

This clinical trial is focused on understanding Klinefelter Syndrome (KS), a genetic condition in males caused by an extra X chromosome. This condition is often linked to infertility, particularly the inability to produce sperm, known as azoospermia. Researchers will take special cells from the testes of KS patients and use a lab technique called an organoid model to study how these cells behave when mixed with different types of supporting cells. The goal is to find out how these interactions might affect fertility in men with KS.

The trial is currently looking for male participants aged 18 to 26 who have been diagnosed with Klinefelter Syndrome. Unfortunately, men with a specific variation of Klinefelter Syndrome known as mosaicism cannot participate. If you join the study, you will help researchers gain insights that could lead to better treatments for infertility related to Klinefelter Syndrome. This is an important step in understanding how to support men with this condition in their journey towards fatherhood.

Gender

MALE

Eligibility criteria

• Inclusion Criteria:
• • Klinefelter
• Exclusion Criteria:
• • Mosaicism