Characterizing Spondyloarthritis With 68Ga-FAPI PET/CT

Launched by THE FIRST AFFILIATED HOSPITAL OF XIAMEN UNIVERSITY · Aug 13, 2023

Keywords

ClinConnect Summary

This clinical trial is studying a new imaging technique called 68Ga-FAPI PET/CT to see how well it can help diagnose spondyloarthritis, a type of inflammatory arthritis that affects the spine and other joints. The researchers want to find out if this method can effectively evaluate inflammation and predict how the condition might progress in patients.

To be eligible for the trial, participants need to be adults aged 18 to 65 who have been diagnosed with spondyloarthritis based on specific criteria. They should also be able to give their consent to join the study. However, pregnant or breastfeeding individuals, those with allergies to the study substance, or anyone with certain medical conditions that could affect their participation won't be able to join. If you decide to participate, you can expect to undergo the 68Ga-FAPI PET/CT scan, which is a special type of imaging that helps doctors see inflammation in your body. This study is currently looking for volunteers, so it could be a chance to contribute to new research that may improve care for people with spondyloarthritis.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. A diagnosis of SpA according to the ASAS (Assessment of Spondyloarthritis International Society) classification criteria for SpA.
• • 2. Adult men or women 18 and ≤ 65 years of age at the time of signing the informed consent (ICF).
• • 3. participants who were able to provide informed consent (signed by participant or legal representative) and assent according to the guidelines of the Clinical Research Ethics Committee.
• Exclusion Criteria:
• • 1. Pregnancy;
• • 2. Breastfeeding;
• • 3. known allergy against FAPI;
• • 4. any medical condition that in the opinion of the investigator may significantly interfere with study compliance.