Needle Free Assessment of Myocardial Oxygenation in Healthy Subjects

Launched by INDIANA UNIVERSITY · Aug 17, 2023

Keywords

ClinConnect Summary

This clinical trial is looking at a new way to assess heart health without using needles. The study will use a special computer-controlled method to see how well the heart is getting enough oxygen, which is important for people who might have coronary artery disease. The goal is to understand if this method is safe and effective in healthy individuals.

To participate, you need to be at least 45 years old and have no known heart disease. Unfortunately, some people won’t be able to join, including those with low blood pressure or certain medical conditions. If you qualify and decide to take part, you will be asked to lie down for 30-40 minutes while your breathing is monitored. This study aims to help improve how doctors can identify heart problems in the future, making it easier and safer for patients.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • 1. Adults ≥ 45 years of age
• • 2. No known cardiac disease
• Exclusion Criteria:
• • 1. Low blood pressure (systolic blood pressure \< 100 mmHg)
• • 2. Inability to voluntarily increase their breathing rate if prompted to do so
• • 3. Persons with the inability to lie supine for 30-40 minutes
• • 4. Persons who are pregnant, nursing, or implanted with intrauterine devices (IUD's)
• • 5. Persons with significant neurological, pulmonary, renal or hepatic disease
• • 6. Persons who have an abnormal cardiac rhythm or resting heart rate \>100/min
• • 7. Inability or unwillingness to provide informed consent