Renal Resistive Index as a Predictor of Acute Kidney Injury and Evaluation of Fluid Administration in Sepsis

Launched by TANTA UNIVERSITY · Aug 19, 2023

Keywords

ClinConnect Summary

This clinical trial is studying the Renal Resistive Index (RRI) to see if it can help predict the development of acute kidney injury (AKI) in patients with sepsis, a serious infection that can lead to organ problems. The researchers will monitor changes in RRI values over a week to see how they relate to AKI. This study aims to improve how we manage fluid treatment for patients with sepsis to protect their kidney function.

To be eligible for this trial, participants must be at least 21 years old and meet specific criteria for sepsis, but they should not be in septic shock. Unfortunately, some individuals cannot participate, such as those who are pregnant, have severe kidney problems, or certain kidney conditions. If you join the study, you can expect close monitoring during your hospital stay, where your kidney function and response to treatment will be carefully evaluated. This research could lead to better care for patients with sepsis in the future.

Gender

ALL

Eligibility criteria

• Inclusion Criteria:
• • Age over 21 years
• • meet Sepsis 3 criteria (potential source of infection , host response and organ dysfunction) but not in septic shock.
• Exclusion Criteria:
• • patients during pregnancy.
• • patients with hepatorenal syndrome.
• • Poor abdominal echogenicity eg.(morbid obesity ,increase intra abdominal pressure )
• • Severe acute or chronic renal insufficiency .
• • Dialysis dependency.
• • Renal transplantation.
• • Known renal artery stenosis.
• • Mono-kidney, kidney tumor, anatomic kidney abnormalities.