Renal Resistive Index as a Predictor of Acute Kidney Injury and Evaluation of Fluid Administration in Sepsis
Launched by TANTA UNIVERSITY · Aug 19, 2023
Trial Information
Current as of July 09, 2025
Recruiting
Keywords
ClinConnect Summary
This clinical trial is studying the Renal Resistive Index (RRI) to see if it can help predict the development of acute kidney injury (AKI) in patients with sepsis, a serious infection that can lead to organ problems. The researchers will monitor changes in RRI values over a week to see how they relate to AKI. This study aims to improve how we manage fluid treatment for patients with sepsis to protect their kidney function.
To be eligible for this trial, participants must be at least 21 years old and meet specific criteria for sepsis, but they should not be in septic shock. Unfortunately, some individuals cannot participate, such as those who are pregnant, have severe kidney problems, or certain kidney conditions. If you join the study, you can expect close monitoring during your hospital stay, where your kidney function and response to treatment will be carefully evaluated. This research could lead to better care for patients with sepsis in the future.
Gender
ALL
Eligibility criteria
- Inclusion Criteria:
- • Age over 21 years
- • meet Sepsis 3 criteria (potential source of infection , host response and organ dysfunction) but not in septic shock.
- Exclusion Criteria:
- • patients during pregnancy.
- • patients with hepatorenal syndrome.
- • Poor abdominal echogenicity eg.(morbid obesity ,increase intra abdominal pressure )
- • Severe acute or chronic renal insufficiency .
- • Dialysis dependency.
- • Renal transplantation.
- • Known renal artery stenosis.
- • Mono-kidney, kidney tumor, anatomic kidney abnormalities.
About Tanta University
Tanta University is a prestigious academic institution located in Egypt, dedicated to advancing medical research and education. As a clinical trial sponsor, Tanta University leverages its extensive resources and expertise to conduct innovative research initiatives aimed at improving health outcomes. The university collaborates with a network of healthcare professionals, researchers, and institutions to facilitate rigorous clinical trials across various medical disciplines. Committed to ethical standards and scientific integrity, Tanta University strives to contribute to the global body of knowledge while fostering the next generation of medical professionals.
Contacts
Jennifer Cobb
Immunology at National Institute of Allergy and Infectious Diseases (NIAID)
Locations
Tanta, Elgharbia, Egypt
Patients applied
Trial Officials
Safinaz A Aboelfetoh, MBBCh
Principal Investigator
Anesthesiology, Faculty of Medicine, Tanta University, Egypt.
Timeline
First submit
Trial launched
Trial updated
Estimated completion
Not reported