Management of Symptomatic Uterine Fibroids in Pregnancy by Laparotomic Myomectomy: a Prospective Cohort Study

Launched by UNIVERSITY OF PALERMO · Aug 19, 2023

Keywords

ClinConnect Summary

This clinical trial is studying how to manage uterine fibroids in pregnant women who are experiencing symptoms. Uterine fibroids are non-cancerous growths in the uterus that can cause discomfort and complications during pregnancy. As more women are found to have both fibroids and pregnancy, doctors need to understand the best ways to treat these patients to ensure a safer pregnancy.

To be eligible for this study, women must have large or giant fibroids that are affecting their ability to continue their pregnancy or causing severe discomfort, such as pain or problems with urination or bowel movements. Women who are interested in participating can expect to undergo a surgical procedure called laparotomic myomectomy, which involves removing the fibroids to help improve their condition. The trial is currently recruiting participants, and it is important to note that women who do not have urgent medical needs for this surgery or who choose not to participate will not be included in the study.

Gender

FEMALE

Eligibility criteria

• Inclusion Criteria:
• • The large and giant size of UFs, which prevent the proper continuation of pregnancy and/or occupy the entire small and large pelvis, as well as invade and/or occupy the abdominal cavity.
• • Circulatory disorders, evidenced by necrosis of the UFs.
• • Atypical localization of UFs (cervical, isthmic, intraligamentary, etc.), which caused pelvic organ dysfunction (dysuric phenomena, tenesmus, impediment to the act of defecation, pelvic pain).
• Exclusion Criteria:
• • Refusal of LPTM by the patient.
• • Absence of urgent indication for LPTM during pregnancy.